Ethnic differences in genetic polymorphism associated with irritable bowel syndrome

Polymorphisms: Genetic variations associated with irritable bowel syndrome.

Diets and Irritable Bowel Syndrome

Introduction: Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder, which is characterized by the presence of abdominal pain or discomfort associated with altered bowel habits. This systematic review aimed to assess the nutritional factors (dietary patterns and food groups) associated with IBS. Methods: Articles were collected ...

Irritable bowel syndrome: methods, mechanisms, and pathophysiology. Genetic epidemiology and pharmacogenetics in irritable bowel syndrome.

The objectives of this review are twofold. Our first objective is to evaluate the evidence supporting a role for genetics in irritable bowel syndrome (IBS). Specific examples of the associations of genetic variation and symptoms, syndromes, and intermediate phenotypes, including neurotransmitter (serotonergic, α(2)-adrenergic, and cannabinoid) mechanisms, inflammatory pathways (IL-10, TNFα, GNβ...

Correlation between DQB1 genetic polymorphism and genetic susceptibility in patients diagnosed with irritable bowel syndrome with diarrhea.

We examined patients of Han nationality diagnosed with irritable bowel syndrome with diarrhea (IBS-D) in Guangdong, China, to analyze the correlation between DQB1 allele polymorphisms and the genetic susceptibility to IBS-D. A total of 120 IBS-D patients of Han nationality in Guangdong, China, and 60 healthy control volunteers were included. DQB1 allele polymorphisms were investigated by polyme...

SOOTHING THE IRRITABLE BOWEL SYNDROME Soothing the Irritable Bowel Syndrome

of patient presentations at gastrointestinal clinics, and up to 50% or more of patients presenting with abdominal symptoms have no organic abnormality detected. The most common functional gastrointestinal conditions in Canada are irritable bowel syndrome (IBS), and functional dyspepsia or nonulcer dyspepsia (NUD). Other functional disorders may affect specific regions of the alimentary tract, s...